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Specialized facilities and career opportunities are available for researchers.
OHSU is known for its basic, clinical, and applied research in the health sciences, including leading approximately 700 clinical trials and operating the Oregon Clinical and Translational Research Institute. The National Institutes of Health (NIH) is OHSU's most significant source of funding, providing close to $230 million in 2017. NIH selected OHSU and PNNL to jointly operate a Metabolomics Core supporting the NIH's Undiagnosed Diseases Network in 2015.
OHSU researchers at the Knight Cancer Institute were the first to demonstrate the success of molecularly targeted chemotherapies in treating cancer. In 2017, the Knight Cancer Institute teamed up with PNNL to collaborate on National Cancer Institute-sponsored clinical trials, focusing on acute myeloid leukemia. Another group in OHSU, the Center for Embryonic Cell and Gene Therapy, pioneers personalized medicine research to repair genes that cause disease.
OHSU's Proteomics Shared Resources makes state-of-the-art mass spectrometry-based protein analysis capabilities available to the biomedical research community at OHSU. See a description of available analytic instruments. Researchers can access one of the strongest MRI magnets in the world at the Advanced Imaging Research Center.
PNNL's Integrated Omics group combines mass spectrometry-based measurements of proteins, metabolites, and lipids with bioinformatics and computational biology to enable a deeper understanding of living systems. To accomplish this ambitious goal, this group develops new technologies in mass spectrometry, chemical biology, and bioinformatics that researchers apply to diverse biological questions.
Through PMedIC, OHSU scientists will be able to access PNNL's advanced computing capacity such as compressive sensing algorithms that improve the analysis of cryoEM images, increasing the speed of analysis without sacrificing resolution. In addition, OHSU scientists will also be able to use PNNL's expertise in analytical approaches to large datasets and the integration of complex molecular data.
The National Cancer Institute, part of the NIH, selected PNNL in 2011 as one of the five premiere proteomics centers in the nation to study protein changes associated with cancer, as part of the Clinical Proteomic Tumor Analysis Consortium. The goal: Develop biomarkers that can be used to guide personalized therapies for individual patients.
PNNL works with nearly 800 scientists annually at the Environmental Molecular Sciences Laboratory (EMSL) , a DOE Office of Science user facility on the PNNL campus that is available to the global research community. At EMSL, PMedIC researchers can access world-class mass instrumentation in mass spectrometry, microscopy, and computing. See a description of EMSL's advanced instruments and take a virtual tour.
Hundreds of graduate students and postdocs with backgrounds in life sciences and other areas of research and technology come through PNNL's doors every year. Check out opportunities for joint appointments, faculty, graduate students, and post graduates, as well as PNNL's Institutional Postdoc Program. Qualified postdocs may want to consider applying for the prestigious Linus Pauling Distinguished Postdoctoral Fellowship and the Wiley Distinguished Postdoctoral Fellowship.
PNNL employs more than 4,000 scientists, engineers, and other professionals who support national missions in fundamental science, energy, and national security. Learn about jobs at PNNL.